Structure of PDB 5tvw Chain A

Receptor sequence
>5tvwA (length=587) Species: 7955 (Danio rerio) [Search protein sequence]
TLHNIITDTENVQGSFSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
GSDALEKLRHRMITAGGDTAPMEIHLQTDSVKGTFTIQDTGVGMNKEDLV
SNLGTIARSGSKAFLDALQNQAEASSSIIGQFGVGFYSAFMVADKVEVYS
QSAEAPGYKWSSDGSGVFEVAEASGVRQGTKIVLHLKDDCKEFSSEDRVK
EVVTKYSNFVSFPIFLNGRRLNTLQALWMMEPKDISEWQHEEFYRYVAQA
YDKPRYTLHYRADAPLNIRSIFYVPEMKPSMFDSSVALYSRKILIQTKAT
DILPKWLRFLRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRVIRFLL
DQSKKDPEKYARFFEDYGLFMREGIVTTGEQSVKEDIAKLLRFESSALPA
GQQTSLMEYSSRMKAGTRNIYYLCAPNRHLAEHSPYFEAMKQKDMEVLFC
FEQFDELTLLHLREFDRKKLISAERLSSEQAEDLLAWMRNALVQRVTNIK
VTPTHPAMITVLEMGAARHFLRLQPTLEINTGHDLIKKLHALKDSNPELA
QLLLEQIYDNAMIAAGLNEDPRPMISRLNQLLTRALE
3D structure
PDB5tvw Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N134 D173 M178 N186 S193 G194 S195 G214 Q215 G217 V218 G219 F220 T266 N50 D89 M94 N102 S109 G110 S111 G130 Q131 G133 V134 G135 F136 T180
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0019901 protein kinase binding
GO:0042802 identical protein binding
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tvw, PDBe:5tvw, PDBj:5tvw
PDBsum5tvw
PubMed28742020
UniProtF1Q9X9

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