Structure of PDB 5tvn Chain A

Receptor sequence
>5tvnA (length=393) Species: 562,9606 [Search protein sequence]
EEMKQIVEEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATN
YFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCPAWLFLDVLFST
ASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPV
PIKGIETNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHA
LQKKAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATP
PKLEPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAY
IQKYLVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTT
LQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR
3D structure
PDB5tvn Crystal Structure of an LSD-Bound Human Serotonin Receptor.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7LD A D135 F217 F340 D95 F174 F333 PDBbind-CN: -logKd/Ki=9.04,Kd=0.91nM
BS02 CLR A I66 G70 Y394 Y399 I26 G30 Y387 Y392
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tvn, PDBe:5tvn, PDBj:5tvn
PDBsum5tvn
PubMed28129538
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P41595|5HT2B_HUMAN 5-hydroxytryptamine receptor 2B (Gene Name=HTR2B)

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