Structure of PDB 5tum Chain A

Receptor sequence
>5tumA (length=369) Species: 450 (Legionella longbeachae) [Search protein sequence]
KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRGIA
THIAREMGIYDQICEMRTRIERGRFVDSSGKVLHEEQGDDEVEILRGDLV
EILMKTIADVPCYFNQSIISIEQNADNVTVIFMDGRIEQYDLVIAADGIH
SAIRRMIFEKNEYQLIHLGAYLSTFTIPNYLGLSHIDLECEANNKLVSIN
SDNNPEIARAGFMFRSQHLLNDIRDEQEQKQFLRDTFRDFGWETQNILNR
MPESNDFYFDAITQVKMNSWTKGRIALVGDAGYCPSPLSGQGNNLAFVGA
YILAGELKVANGNYTRAFTRYNALLRSFVDANQKFGVWVSESFEERSNKI
LAMIKSISNGITLPQYESS
3D structure
PDB5tum Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
ChainA
Resolution3.299 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G11 A15 E34 K35 R40 G42 Q44 R105 A155 D156 G157 Y267 D289 P296 G9 A13 E32 K33 R38 G40 Q42 R96 A146 D147 G148 Y258 D280 P287
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0071949 FAD binding
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:5tum, PDBe:5tum, PDBj:5tum
PDBsum5tum
PubMed28481346
UniProtD3HKY4|TET56_LEGLN Flavin-dependent monooxygenase (Gene Name=tet(56))

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