Structure of PDB 5tui Chain A

Receptor sequence
>5tuiA (length=388) Species: 77133 (uncultured bacterium) [Search protein sequence]
MTKHIKILVIGVGVAGPAVAYWLKRFGFSPVLIEKSAAVRKGGQALDIRG
IATHIAKEMGIYDQICNMRTQIKCGRYVDVKGNVLHEEQGETFGFRQDDE
VEILRGDLVEILMKAIADIPCEFKQSVIKIEQNEDSVTVTYKDGRVENYD
LVIAADGIHSATRGMVFSKNEYQLINLGSYVSAFTIPNYLGLDHMELLCE
SNHKLVTLQSDSQADKAMAGFMFRSKHVLEDIRDEQEQKHFLHASFQNFG
WETQNILNRMPESDDFYFDAITQIKMKSWTKGRIALIGDAAYCPSPLSGQ
GNNLAFVGAYILAGELKKADGDYIQAFTRYNELLHPFVEANQQFGVWVSE
SFLLKDDEVSKEIAEARSNKILAMIKSVSNSINLPQYE
3D structure
PDB5tui Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A I10 V12 G13 V14 A15 E34 K35 Q44 A45 L46 D47 R105 D156 Y267 G288 D289 P296 G299 G301 N302 I10 V12 G13 V14 A15 E34 K35 Q44 A45 L46 D47 R105 D156 Y267 G288 D289 P296 G299 G301 N302
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0071949 FAD binding
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5tui, PDBe:5tui, PDBj:5tui
PDBsum5tui
PubMed28481346
UniProtA0A059WYP6|TET50_UNKP Flavin-dependent monooxygenase (Gene Name=tet(50))

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