Structure of PDB 5tua Chain A

Receptor sequence
>5tuaA (length=627) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
QKAAALVDLAEDGIGLPVEILDFGESARYYFIFTRLDLIWSLNYFALLFL
NFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVH
TFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYFRIAPYVRVII
FILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQG
LTVFTSYGATLYQMFILFTTANNPDVWIPAYKSSRWSSVFFVLYVLIGVY
FVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDK
NQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQA
IALRFQKEEVPQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVET
TLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDF
LVTWVIVIGETATFITPFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIA
TFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLGNKKLFETELAEDDYL
LFNFNDYPNGMVTLFNLLVVNNWQVWMESYKDLTGTWWSITYFVSFYVIT
ILLLLNLVVAFVLEAFFTELDLEEEEK
3D structure
PDB5tua Tuning the ion selectivity of two-pore channels.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D335 D337 N339 E341 D291 D293 N295 E297
BS02 CA A W92 E124 D166 D170 W58 E90 D132 D136
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0042802 identical protein binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0006816 calcium ion transport
GO:0009845 seed germination
GO:0010119 regulation of stomatal movement
GO:0019722 calcium-mediated signaling
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0080141 regulation of jasmonic acid biosynthetic process
Cellular Component
GO:0000325 plant-type vacuole
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0034702 monoatomic ion channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tua, PDBe:5tua, PDBj:5tua
PDBsum5tua
PubMed28096396
UniProtQ94KI8|TPC1_ARATH Two pore calcium channel protein 1 (Gene Name=TPC1)

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