Structure of PDB 5tt6 Chain A

Receptor sequence
>5tt6A (length=375) Species: 10665 (Tequatrovirus T4) [Search protein sequence]
HMQELFNNLMELCKDSQRKFFYSDDVSASGRTYRIFSYNYASYSDWLLPD
ALECRGIMFEMDGEKPVRIASRPMEKFFNLNENPFTMNIDLNDVDYILTM
EDGSLVSTYLDGDEILFKSKGSIKSEQALMANGILMNINHHRLRDRLKEL
AEDGFTANFEFVAPTNRIVLAYQEMKIILLNVRENETGEYISYDDIYKDA
TLRPYLVERYEIDSPKWIEEAKNAENIEGYVAVMKDGSHFKIKSDWYVSL
HSTKSSLDNPEKLFKTIIDGASDDLKAMYADDEYSYRKIEAFETTYLKYL
DRALFLVLDCHNKHCGKDRKTYAMEAQGVAKGAGMDHLFGIIMSLYQGYD
SQEKVMCEIEQNFLKNYKKFIPEGY
3D structure
PDB5tt6 Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
ChainA
Resolution2.187 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.3: RNA ligase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A Y37 R54 M73 K75 M99 E100 L104 E159 L179 V230 K240 K242 Y38 R55 M74 K76 M100 E101 L105 E160 L180 V231 K241 K243
Gene Ontology
Molecular Function
GO:0003972 RNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0042245 RNA repair
GO:0098004 virus tail fiber assembly

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5tt6, PDBe:5tt6, PDBj:5tt6
PDBsum5tt6
PubMed28223499
UniProtP00971|RLIG_BPT4 RNA ligase 1 (Gene Name=63)

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