Structure of PDB 5trd Chain A

Receptor sequence

>5trdA (length=219) Species: 273075 (Thermoplasma acidophilum DSM 1728) [Search protein sequence]

DQYYRAIKKIKEAAEASNRAYLTSSKLADMLGISQQSASRIIIDLEKNGY
ITRTVTKRGQILNITEKGLDVLYTEFADLSRILAIKNNVVITGTVTSGMG
EGRYYVARKQYIIQFQEKLGIIPYLGTLNIKVDQASLPELRKIRGFRGIH
IEGFKTEDRTFGSVKAFPAKIQNIPCFVIMPERTVYTDVIEIISDKYLRE
EINLHDGDRVSVEVYTEGH

3D structure

PDB

5trd Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex with CTP and its cognate DNA operator

Chain

Resolution

1.85 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.1.161: CTP-dependent riboflavin kinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	S38 Q40 S41 R44	S34 Q36 S37 R40
BS02	dna	A	T27 S28 Q39 Q40 S43 I47 R57 V59 K61 Q64	T23 S24 Q35 Q36 S39 I43 R53 V55 K57 Q60
BS03	CTP	A	G102 M103 G104 E105 G106 R107 Y128 G130 T131 L132 N133 K200 Y201 L202 R203	G98 M99 G100 E101 G102 R103 Y124 G126 T127 L128 N129 K196 Y197 L198 R199

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0008531	riboflavin kinase activity
GO:0016301	kinase activity
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0046872	metal ion binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0009231	riboflavin biosynthetic process
GO:0009398	FMN biosynthetic process
GO:0016310	phosphorylation

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Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:5trd, PDBe:5trd, PDBj:5trd
PDBsum	5trd
PubMed
UniProt	Q9HJA6\|RIFK_THEAC Riboflavin kinase (Gene Name=ribK)

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