Structure of PDB 5tpk Chain A

Receptor sequence
>5tpkA (length=202) Species: 10090 (Mus musculus) [Search protein sequence]
NDNAPVFDPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNFN
NLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVL
DIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRSPE
VKHLFALHPFTGELSLLRSLDYEASITFLAEAFDIYGTMPPGIATVTVIV
KD
3D structure
PDB5tpk Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E708 E709 N757 E759 D793 E19 E20 N68 E70 D104
BS02 CA A E708 E759 D790 I791 D793 D826 E19 E70 D101 I102 D104 D137
BS03 CA A D792 N794 D824 D826 D103 N105 D135 D137
BS04 CA A N690 N692 D722 D724 N728 D772 N1 N3 D33 D35 N39 D83
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tpk, PDBe:5tpk, PDBj:5tpk
PDBsum5tpk
PubMed32963095
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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