Structure of PDB 5too Chain A

Receptor sequence
>5tooA (length=517) Species: 238 (Elizabethkingia meningoseptica) [Search protein sequence]
NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHID
YVPTVSAIGHTSIFTGSVPSIHGIAGADWYDKELGKSVYCTSDETVQPVG
TTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLADAASILPAGHN
PTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLP
INQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNT
LTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYL
RLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFM
KKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTE
LKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYL
SSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLK
IQFPSGAVGKPITEVIG
3D structure
PDB5too Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution.
ChainA
Resolution2.031 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.1: alkaline phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D38 D352 H353 D15 D329 H330
BS02 ZN A D305 H309 H486 D282 H286 H458
BS03 ZN A D233 E238 E317 D210 E215 E294
BS04 ZN A D291 D295 D268 D272
Gene Ontology
Molecular Function
GO:0004035 alkaline phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:5too, PDBe:5too, PDBj:5too
PDBsum5too
PubMed29070681
UniProtQ9KJX5|ALPH_ELIME Alkaline phosphatase PafA (Gene Name=pafA)

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