Structure of PDB 5tn5 Chain A

Receptor sequence
>5tn5A (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5tn5 Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainA
Resolution1.892 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 N359 K362 R363 L372 V376 E380 D538 L539 E542 I55 N56 K59 R60 L69 V73 E77 D225 L226 E229
BS02 7G0 A E353 F404 H524 E50 F101 H211
External links
PDB RCSB:5tn5, PDBe:5tn5, PDBj:5tn5
PDBsum5tn5
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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