Structure of PDB 5tn1 Chain A

Receptor sequence
>5tn1A (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
SKKNSLALSLTADQMVSALLDAEPPILYSEYRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQR
LAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5tn1 Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainA
Resolution2.055 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 D538 L539 E542 I55 K59 L69 V73 D235 L236 E239
BS02 7FR A L346 E353 G521 H524 L43 E50 G218 H221
External links
PDB RCSB:5tn1, PDBe:5tn1, PDBj:5tn1
PDBsum5tn1
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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