Structure of PDB 5tmu Chain A

Receptor sequence
>5tmuA (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5tmu Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainA
Resolution2.429 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 L379 E380 D538 L539 E542 I54 K58 L68 V72 L75 E76 D231 L232 E235
BS02 7FL A L346 T347 A350 E353 L387 M421 I424 L525 L42 T43 A46 E49 L83 M117 I120 L218
External links
PDB RCSB:5tmu, PDBe:5tmu, PDBj:5tmu
PDBsum5tmu
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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