Structure of PDB 5tmm Chain A

Receptor sequence
>5tmmA (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTF
KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKG
MEHLYSMKCKLSDLLLEMLDAHR
3D structure
PDB5tmm Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 L379 D538 E542 M543 I49 K53 V67 L70 D213 E217 M218
BS02 7M4 A L346 T347 E353 L387 L391 F404 M421 L525 L37 T38 E44 L78 L82 F95 M110 L204
External links
PDB RCSB:5tmm, PDBe:5tmm, PDBj:5tmm
PDBsum5tmm
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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