Structure of PDB 5tm2 Chain A

Receptor sequence
>5tm2A (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINWA
KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLD
RNQGKCMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKDHI
HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL
YSMKCPLSDLLLEMLDA
3D structure
PDB5tm2 Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainA
Resolution2.603 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 V376 D538 E542 I47 V65 D209 E213
BS02 7EO A M343 E353 L387 M421 M32 E42 L76 M107
External links
PDB RCSB:5tm2, PDBe:5tm2, PDBj:5tm2
PDBsum5tm2
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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