Structure of PDB 5tgd Chain A

Receptor sequence

>5tgdA (length=249) Species: 1160233 (Brucella suis 92/29) [Search protein sequence]

EARMVANCPVLVTGGARRIGKAIVEDLASHGFPVAIHCNRSLDEGEAIAN
RINDSGGNACVVQADLEGDVRGLVKQASDRIGPIRLLVNNASLFQEDKVG
ALDMALWDRHFAVHLKTPVILAEDMRKALPEDQDGLVVNIIDQRVWKLNP
QFFSYTLSKSALWNATRTLAQALAPRIRVNAIAPGPTLPSERQRPEDFER
QVSKLPLQRAPELPEFGRTVRYFWENRSITGQMIALDGGQHLAWETPDI

3D structure

PDB

5tgd Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis.

Chain

Resolution

1.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	A	R31 I32 H50 C51 N52 R53 S54 D78 L79 E80 N103 A104 S105 I153 I154 K172 P197 G198 T200 L201	R18 I19 H37 C38 N39 R40 S41 D65 L66 E67 N90 A91 S92 I140 I141 K159 P184 G185 T187 L188

External links

PDB	RCSB:5tgd, PDBe:5tgd, PDBj:5tgd
PDBsum	5tgd
PubMed	34981773

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