Structure of PDB 5tfl Chain A

Receptor sequence
>5tflA (length=202) Species: 10090 (Mus musculus) [Search protein sequence]
PPTFSKPAYFVSVLENIMAGATVLFLNATDSIIYSLEGSSQFRINARSGE
ITTTSLLDRETKSEYILIVRAVDNQKTGIATVNVTLLDINDNHPTWKDAP
YYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHPPNKFYSLNSTTGK
IRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLD
LN
3D structure
PDB5tfl Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
ChainA
Resolution3.56 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E659 E714 D747 I748 D750 D783 E15 E60 D88 I89 D91 D124
BS02 CA A N749 N751 D781 D783 N787 D839 N90 N92 D122 D124 N128 D180
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tfl, PDBe:5tfl, PDBj:5tfl
PDBsum5tfl
PubMed30033219
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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