Structure of PDB 5t9t Chain A

Receptor sequence

>5t9tA (length=526) Species: 10090 (Mus musculus) [Search protein sequence]

DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPE
SGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNA
PLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEV
TEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRI
QVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYA
FHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASH
CSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENG
DVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKP
PLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPD
LGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQL
TLQARDHGSPTLSANVSMRVLVGDRN

3D structure

PDB

5t9t gamma-Protocadherin structural diversity and functional implications.

Chain

Resolution

3.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CA	A	E9 E10 D61 E63 D98	E9 E10 D61 E63 D98
BS02	CA	A	E9 E63 D95 V96 D98 D131	E9 E63 D95 V96 D98 D131
BS03	CA	A	N97 N99 D129 D131 N135 D186	N97 N99 D129 D131 N135 D186
BS04	CA	A	E114 D171 E173 D207	E114 D171 E173 D207
BS05	CA	A	E114 E173 D204 I205 D207 D240	E114 E173 D204 I205 D207 D240
BS06	CA	A	N206 N208 D238 D240 N244 D293	N206 N208 D238 D240 N244 D293
BS07	CA	A	E223 D278 E280 D312	E223 D278 E280 D312
BS08	CA	A	E223 E280 D309 E310 D312 D345	E223 E280 D309 E310 D312 D345
BS09	CA	A	N311 C313 D343 D345 N349 D396	N311 C313 D343 D345 N349 D396
BS10	CA	A	E328 D381 E383 D417	E328 D381 E383 D417
BS11	CA	A	E328 E383 D414 V415 D417 D450	E328 E383 D414 V415 D417 D450
BS12	CA	A	N416 N418 D448 D450 N454 D506	N416 N418 D448 D450 N454 D506
BS13	MAN	A	S230 Q233	S230 Q233
BS14	MAN	A	S440 A442 Q443	S440 A442 Q443
BS15	MAN	A	V181 T195	V181 T195
BS16	MAN	A	S403 N405	S403 N405

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5t9t, PDBe:5t9t, PDBj:5t9t
PDBsum	5t9t
PubMed	27782885
UniProt	Q8K486

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