Structure of PDB 5t9f Chain A

Receptor sequence
>5t9fA (length=249) Species: 3847 (Glycine max) [Search protein sequence]
SLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDV
SAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRE
LLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDKVRIRDEVICSNFI
QIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKG
FETLVKLKETMMRDSFDLYSGLFVYNRFARQELENLEHALHKVKETLMI
3D structure
PDB5t9f Molecular basis of the evolution of alternative tyrosine biosynthetic routes in plants.
ChainA
Resolution1.994 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.13: prephenate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G16 G18 N19 F20 S39 R40 S41 Y43 C72 T73 S74 S77 V99 L100 S101 S223 G8 G10 N11 F12 S31 R32 S33 Y35 C64 T65 S66 S69 V91 L92 S93 S215
BS02 TYR A S101 H124 F127 G128 Q130 T131 Q184 H188 D222 S93 H116 F119 G120 Q122 T123 Q176 H180 D214 MOAD: ic50=4.7mM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004665 prephenate dehydrogenase (NADP+) activity
GO:0008977 prephenate dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0033730 arogenate dehydrogenase (NADP+) activity
GO:0070403 NAD+ binding
Biological Process
GO:0006571 tyrosine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5t9f, PDBe:5t9f, PDBj:5t9f
PDBsum5t9f
PubMed28671678
UniProtI1MYY4

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