Structure of PDB 5t70 Chain A

Receptor sequence
>5t70A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB5t70 MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 N66 S70 T73 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 L156 Y159 W167 Y171 Y7 E63 N66 S70 T73 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 L156 Y159 W167 Y171
External links
PDB RCSB:5t70, PDBe:5t70, PDBj:5t70
PDBsum5t70
PubMed28218747
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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