Structure of PDB 5t4m Chain A

Receptor sequence
>5t4mA (length=347) Species: 9606 (Homo sapiens) [Search protein sequence]
SPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDR
NIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKF
DLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVG
ATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITR
YLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPE
ISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIINKT
TGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP
3D structure
PDB5t4m A Partial Calcium-Free Linker Confers Flexibility to Inner-Ear Protocadherin-15.
ChainA
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E367 N369 D411 E127 N129 D171
BS02 CA A N368 Q370 D409 D411 D464 N128 Q130 D169 D171 D224
BS03 CA A E385 D449 E451 D483 E145 D209 E211 D243
BS04 CA A E385 E451 D480 A481 D483 D516 E145 E211 D240 A241 D243 D276
BS05 CA A N482 N484 D514 D516 N520 D566 N242 N244 D274 D276 N280 D326
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5t4m, PDBe:5t4m, PDBj:5t4m
PDBsum5t4m
PubMed28238533
UniProtQ96QU1|PCD15_HUMAN Protocadherin-15 (Gene Name=PCDH15)

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