Structure of PDB 5t3n Chain A

Receptor sequence
>5t3nA (length=153) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
HHEVLFQGPGAKKRKMYEDILSHVNILKDMDPYERCKVADCLKSKSYNDG
EIIIKEGEEGDTFFILIDGNAVASKDNKVIKTYTKGDYFGELALLKNKPR
AATIKAQNFCQVVYLDRKSFKRLLGPIEDILHRNVENYKKVLNELGLDTT
CID
3D structure
PDB5t3n Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.11: cAMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 75G A I366 Y369 F375 G376 E377 L378 A379 R386 A387 I390 Y424 L428 I438 I80 Y83 F89 G90 E91 L92 A93 R100 A101 I104 Y138 L142 I152 MOAD: Kd=9.1nM
PDBbind-CN: -logKd/Ki=8.04,Kd=9.1nM
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