Structure of PDB 5t2t Chain A

Receptor sequence
>5t2tA (length=189) [Search protein sequence]
HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCI
EIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLIL
LECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNS
FMPEWANFKFRDLLFKLLEYSNQDEKVFEESEYFRLCES
3D structure
PDB5t2t Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
ChainA
Resolution1.967 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D88 C102 D89 C103
BS02 0N8 A K43 R47 L84 I86 D88 K114 K44 R48 L85 I87 D89 K115 PDBbind-CN: -logKd/Ki=6.29,Kd=0.51uM
External links
PDB RCSB:5t2t, PDBe:5t2t, PDBj:5t2t
PDBsum5t2t
PubMed29765612
UniProtP14240|L_LYCVA RNA-directed RNA polymerase L (Gene Name=L)

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