Structure of PDB 5t0x Chain A

Receptor sequence

>5t0xA (length=148) Species: 8355 (Xenopus laevis) [Search protein sequence]

ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD
MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI
SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

3D structure

PDB

5t0x Solution NMR-derived structure of calmodulin bound with ER alpha peptides

Chain

Resolution

N/A

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	V35
Catalytic site (residue number reindexed from 1)	V35
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	E11 F12 E14 L18 F19 I27 M36 L39 M51 E54 V55 I63 F68 M71 M72	E11 F12 E14 L18 F19 I27 M36 L39 M51 E54 V55 I63 F68 M71 M72
BS02	peptide	A	E84 E87 A88 F92 I100 L105 M109 L112 E120 E123 M124 I125 E127 A128 V136 F141 M144 M145	E84 E87 A88 F92 I100 L105 M109 L112 E120 E123 M124 I125 E127 A128 V136 F141 M144 M145
BS03	CA	A	D20 D22 D24 T26 E31	D20 D22 D24 T26 E31
BS04	CA	A	D56 D58 N60 T62 D64 E67	D56 D58 N60 T62 D64 E67
BS05	CA	A	D93 D95 N97 Y99 E104	D93 D95 N97 Y99 E104
BS06	CA	A	D129 D131 D133 Q135 E140	D129 D131 D133 Q135 E140

Gene Ontology

	Molecular Function
GO:0005102	signaling receptor binding
GO:0005509	calcium ion binding
GO:0030234	enzyme regulator activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:5t0x, PDBe:5t0x, PDBj:5t0x
PDBsum	5t0x
PubMed
UniProt	P0DP33\|CALM1_XENLA Calmodulin-1 (Gene Name=calm1)

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