Structure of PDB 5sw9 Chain A

Receptor sequence
>5sw9A (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]
ADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRN
VITEPIYPEVVHMFAVNMFRTLPPEAAWPHLQLVYEFFLRFLESPDFQPN
IAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQ
INNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLP
LHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVM
FLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNE
YIMSLISDNAAKILPIMFPSLYRN
3D structure
PDB5sw9 Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
ChainA
Resolution2.846 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A H187 R188 Y190 L194 R197 R201 S230 N233 G234 F235 A236 H243 H134 R135 Y137 L141 R144 R148 S177 N180 G181 F182 A183 H190
Gene Ontology
Molecular Function
GO:0019888 protein phosphatase regulator activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0000159 protein phosphatase type 2A complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5sw9, PDBe:5sw9, PDBj:5sw9
PDBsum5sw9
PubMed27998540
UniProtQ13362|2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Gene Name=PPP2R5C)

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