Structure of PDB 5svb Chain A

Receptor sequence
>5svbA (length=746) Species: 78245 (Xanthobacter autotrophicus Py2) [Search protein sequence]
TRGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKLFSR
LRAGVVDARETAKKIAAEGELCFTLYNAAGDSLLTSTGIIIHVGTMGAAI
KYMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPIFWEGELIGW
VGGVTHVIDTGATGQVQRYSITCRKVGANDTLFRDWLHESQRMVRTTRYW
MLDERTRIAGCHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRLGLQARIK
AMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDTIMHAPCEMTIRRDGTW
RLDFEGSSRWGWHTYNAHQVSFTSGIWVMMTQTLIPSEMINDGAAYGTEF
RLPKGTWMNPDDRRVAFSYSWHFLVSAWTALWRGLSRSYFGRGYLEEVNA
GNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVQDGLSHAAAIWN
PEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKYRGGCGFESLRMVWNAK
DWTMFFMGNGHISSDWGLMGGYPAASGYRFAAHKTNLKELIASGAEIPLG
GDTDPENPTWDAMLPDAQIKRDKQAITTEEMFSDYDLYLNYMRGGPGFGD
PLDREPQAVADDINGGYVLERFAGEVYGVVVRKGADGQYGVDEAGTAAAR
AQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQVRQMFAASFKLGPRFEK
DFRTFWSLPDSWTLPEEEIGVPTYGSRYSMDISELPDVHTVQFVEE
3D structure
PDB5svb Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation.
ChainA
Resolution2.645 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.4.1.6: acetone carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E89 H150 D153 H175 E70 H131 D134 H156
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016874 ligase activity
GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity
GO:0018710 acetone carboxylase activity
Biological Process
GO:0006749 glutathione metabolic process
GO:0140977 cellular detoxification of acetone
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5svb, PDBe:5svb, PDBj:5svb
PDBsum5svb
PubMed28775283
UniProtQ8RM03|ACXB_XANP2 Acetone carboxylase alpha subunit (Gene Name=acxB)

[Back to BioLiP]