Structure of PDB 5sb2 Chain A

Receptor sequence
>5sb2A (length=286) Species: 9606 (Homo sapiens) [Search protein sequence]
VDFPRSRLRFKEKLGEGQFGEVHLCEVDSVRKGHPLLVAVKILRPDATKN
ARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS
AHQLEDKADPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGE
NFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDV
WAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC
PQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNT
3D structure
PDB5sb2 Crystal Structure of a DDR1 complex
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1K2 A L616 V624 A653 E672 M676 L679 I685 M699 T701 M704 L767 A777 D778 F779 L14 V22 A39 E58 M62 L65 I71 M85 T87 M90 L147 A157 D158 F159
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5sb2, PDBe:5sb2, PDBj:5sb2
PDBsum5sb2
PubMed
UniProtQ08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (Gene Name=DDR1)

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