Structure of PDB 5sb1 Chain A

Receptor sequence
>5sb1A (length=284) Species: 9606 (Homo sapiens) [Search protein sequence]
DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQPLLVAVKILRPDATKNARND
FLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQL
EDKAADPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFT
IKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAF
GVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQG
LYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV
3D structure
PDB5sb1 Crystal Structure of a DDR1 complex
ChainA
Resolution1.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1JI A A653 K655 E672 M676 L679 T701 Y703 M704 H758 L767 A777 D778 F779 A35 K37 E54 M58 L61 T83 Y85 M86 H135 L144 A154 D155 F156
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5sb1, PDBe:5sb1, PDBj:5sb1
PDBsum5sb1
PubMed
UniProtQ08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (Gene Name=DDR1)

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