Structure of PDB 5saz Chain A

Receptor sequence
>5sazA (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
VDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSHPLLVAVKILRPDAT
KNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQF
LSAHQLEDKAADPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCL
VGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTA
SDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRP
PACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV
3D structure
PDB5saz Crystal Structure of a DDR1 complex
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1IW A V624 A653 K655 E672 M676 I685 T701 M704 L767 A777 D778 F779 V22 A41 K43 E60 M64 I73 T89 M92 L150 A160 D161 F162
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5saz, PDBe:5saz, PDBj:5saz
PDBsum5saz
PubMed
UniProtQ08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (Gene Name=DDR1)

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