Structure of PDB 5say Chain A

Receptor sequence
>5sayA (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
RVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSHPLLVAVKILRPDA
TKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ
FLSAHQLEDKAAEGAPGDPTISYPMLLHVAAQIASGMRYLATLNFVHRDL
ATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILM
GKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQ
VYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAE
3D structure
PDB5say Crystal Structure of a DDR1 complex
ChainA
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1IJ A A653 E672 M676 L679 I685 Y703 M704 H758 A777 D778 F779 A42 E61 M65 L68 I74 Y92 M93 H147 A166 D167 F168
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5say, PDBe:5say, PDBj:5say
PDBsum5say
PubMed
UniProtQ08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (Gene Name=DDR1)

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