Structure of PDB 5sax Chain A

Receptor sequence
>5saxA (length=302) Species: 9606 (Homo sapiens) [Search protein sequence]
PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPGHPLLVAVK
ILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYME
NGDLNQFLSAHQLEDKAAEGAPGDPTISYPMLLHVAAQIASGMRYLATLN
FVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMA
WECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFF
RDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALN
TV
3D structure
PDB5sax Crystal Structure of a DDR1 complex
ChainA
Resolution1.902 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1IM A K655 E672 M676 L679 I685 T701 M704 A777 D778 K50 E67 M71 L74 I80 T96 M99 A172 D173
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5sax, PDBe:5sax, PDBj:5sax
PDBsum5sax
PubMed
UniProtQ08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (Gene Name=DDR1)

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