Structure of PDB 5qu2 Chain A

Receptor sequence
>5qu2A (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
EVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPS
NYVERK
3D structure
PDB5qu2 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
ChainA
Resolution1.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F9 Q15 E18 K34 S35 W36 F48 P50 N52 Y53 F8 Q14 E17 K33 S34 W35 F47 P49 N51 Y52
External links
PDB RCSB:5qu2, PDBe:5qu2, PDBj:5qu2
PDBsum5qu2
PubMed32317279
UniProtP16333|NCK1_HUMAN SH2/SH3 adapter protein NCK1 (Gene Name=NCK1)

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