Structure of PDB 5qc9 Chain A

Receptor sequence
>5qc9A (length=221) Species: 9606 (Homo sapiens) [Search protein sequence]
ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLS
AQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKC
QYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYR
SGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMA
RNKGNHCGIASFPSYPEILQG
3D structure
PDB5qc9 Crystal structure of human Cathepsin-S with bound ligand
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q19 S25 H164 N184
Catalytic site (residue number reindexed from 1) Q20 S26 H165 N185
Enzyme Commision number 3.4.22.27: cathepsin S.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BG7 A K64 G68 G69 F70 M71 V162 H164 G165 F211 K65 G69 G70 F71 M72 V163 H165 G166 F212
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5qc9, PDBe:5qc9, PDBj:5qc9
PDBsum5qc9
PubMed
UniProtP25774|CATS_HUMAN Cathepsin S (Gene Name=CTSS)

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