Structure of PDB 5oy2 Chain A

Receptor sequence
>5oy2A (length=327) [Search protein sequence]
EPGLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPR
NGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTR
LTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVD
YSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFP
ANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQA
HPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQL
RKALNTNLDFLFQGVAAGCTQVFPYGR
3D structure
PDB5oy2 Structural Insights into the Substrate Promiscuity of a Laboratory-Evolved Peroxygenase.
ChainA
Resolution1.36 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.11.2.1: unspecific peroxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A C36 P37 G38 L39 V63 F67 F69 T78 F121 E122 G123 S126 M127 T128 R189 E196 F199 L203 F204 C36 P37 G38 L39 V63 F67 F69 T78 F121 E122 G123 S126 M127 T128 R189 E196 F199 L203 F204
BS02 MG A E122 G123 S126 E122 G123 S126
BS03 3DM A A77 F121 T192 E196 F199 A77 F121 T192 E196 F199
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5oy2, PDBe:5oy2, PDBj:5oy2
PDBsum5oy2
PubMed30376293
UniProtB9W4V6|APO1_CYCAE Aromatic peroxygenase (Gene Name=APO1)

[Back to BioLiP]