Structure of PDB 5oxu Chain A

Receptor sequence
>5oxuA (length=325) [Search protein sequence]
GLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNG
VATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLT
GPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYS
NRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPAN
LFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHP
MQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRK
ALNTNLDFLFQGVAAGCTQVFPYGR
3D structure
PDB5oxu Structural Insights into the Substrate Promiscuity of a Laboratory-Evolved Peroxygenase.
ChainA
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.2.1: unspecific peroxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A C36 P37 G38 L39 V63 F67 F69 T78 F121 E122 G123 S126 M127 T128 R189 E196 F199 L203 F204 C34 P35 G36 L37 V61 F65 F67 T76 F119 E120 G121 S124 M125 T126 R187 E194 F197 L201 F202
BS02 MG A E122 G123 S126 E120 G121 S124
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification

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Molecular Function
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Biological Process
External links
PDB RCSB:5oxu, PDBe:5oxu, PDBj:5oxu
PDBsum5oxu
PubMed30376293
UniProtB9W4V6|APO1_CYCAE Aromatic peroxygenase (Gene Name=APO1)

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