Structure of PDB 5owf Chain A

Receptor sequence
>5owfA (length=235) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
QTVRIGTDTTYAPFSSKDAKGEFIGFDIDLGNEMCKRMQVKCTWVASDFD
ALIPSLKAKKIDAIISSLSITDKRQQEIAFSDKLYAADSRLIAAKGSPIQ
PTLESLKGKHVGVKQGSTQEAYANDNWRTKGVDVVAYANQDLIYSDLTAG
RLDAALQDEVAASEGFLKQPAGKEYAFAGPSVKDKKYFGDGTGVGLRKDD
TELKAAFDKALTELRQDGTYDKMAKKYFDFNVYGD
3D structure
PDB5owf Redesign of LAOBP to bind novel l-amino acid ligands.
ChainA
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLN A Y35 F73 S90 S91 S93 R98 K138 S141 T142 D182 Y11 F49 S66 S67 S69 R74 K114 S117 T118 D158 MOAD: Kd=1.59uM
PDBbind-CN: -logKd/Ki=5.80,Kd=1.59uM
Gene Ontology
Biological Process
GO:0006865 amino acid transport
GO:0071705 nitrogen compound transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5owf, PDBe:5owf, PDBj:5owf
PDBsum5owf
PubMed29524280
UniProtP02911|ARGT_SALTY Lysine/arginine/ornithine-binding periplasmic protein (Gene Name=argT)

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