Structure of PDB 5oqd Chain A

Receptor sequence
>5oqdA (length=184) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
RVNEEQIYCYCGKPGKFDHNMLQCCKCRNWFHTQCMQNFKKKLLRGDMFF
VFCCTVCNNGIEFVRRMQIEWVDVLHIALYNLRKQHKYHHLLNDIWPFIL
EQRHQLPICEKWRTLPETALMERLKQTLKDYSDRFVCGREFKRAPAFYAL
RHSGPPHIPKVFLEPHEELSDELLEKRFKLMLMP
3D structure
PDB5oqd DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation.
ChainA
Resolution2.447 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C515 C517 H538 C541 C9 C11 H32 C35
BS02 ZN A C530 C533 C560 C563 C24 C27 C54 C57
External links
PDB RCSB:5oqd, PDBe:5oqd, PDBj:5oqd
PDBsum5oqd
PubMed29058710
UniProtQ24459|PCL_DROME Polycomb protein Pcl (Gene Name=Pcl)

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