Structure of PDB 5onb Chain A

Receptor sequence
>5onbA (length=270) Species: 9606 (Homo sapiens) [Search protein sequence]
MLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAA
LLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHI
PLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIP
LCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGK
MVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQV
LKDDTTTKRWLAQLVKNLQE
3D structure
PDB5onb DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R46 E47 A84 H85 N88 Q98 R130 E133 Y134 L137 T138 G141 G144 K148 L177 F184 K230 R31 E32 A69 H70 N73 Q83 R115 E118 Y119 L122 T123 G126 G129 K133 L162 F169 K215
Gene Ontology
Biological Process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0030014 CCR4-NOT complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5onb, PDBe:5onb, PDBj:5onb
PDBsum5onb
PubMed29255063
UniProtQ92600|CNOT9_HUMAN CCR4-NOT transcription complex subunit 9 (Gene Name=CNOT9)

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