Structure of PDB 5olz Chain A

Receptor sequence
>5olzA (length=387) Species: 562,9606 [Search protein sequence]
GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSL
AAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAI
AIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQ
PKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYL
RIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDA
QKKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYL
ERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLW
LMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS
3D structure
PDB5olz Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T4E A V84 F168 E169 M177 W246 L249 H250 N253 H278 V86 F170 E171 M179 W328 L331 H332 N335 H360 MOAD: Kd=250pM
BS02 CLR A H75 G76 H77 G78
BS03 CLR A A72 A73 G76 A74 A75 G78
BS04 CLR A P248 S263 P330 S345
BS05 CLR A C254 F255 F258 C259 C336 F337 F340 C341
Gene Ontology
Molecular Function
GO:0001609 G protein-coupled adenosine receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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External links
PDB RCSB:5olz, PDBe:5olz, PDBj:5olz
PDBsum5olz
PubMed29311713
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P29274|AA2AR_HUMAN Adenosine receptor A2a (Gene Name=ADORA2A)

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