Structure of PDB 5ok6 Chain A

Receptor sequence
>5ok6A (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
HEELPGLDSQWRQIENGESGRERPLRAGESWFLVEKHWYKQWEAYVQGGD
QDSSTFPGCINNATLFQDEINWRLKEGLVEGEDYVLLPAAAWHYLVSWYG
LEHGQPPIERKVIELPNIQKVEVYPVELLLVRHNDLGKSHTVQFSHTDSI
GLVLRTARERFLVEPQEDTRLWAKNSEGSLDRLYDTHITVLDAALETGQL
IIMETRKKDGTWPSAQLEH
3D structure
PDB5ok6 Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11.
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H161 W200 N203 S207 L208 D209 L245 E246 H247 H133 W172 N175 S179 L180 D181 L217 E218 H219
Gene Ontology
Molecular Function
GO:0004843 cysteine-type deubiquitinase activity

View graph for
Molecular Function
External links
PDB RCSB:5ok6, PDBe:5ok6, PDBj:5ok6
PDBsum5ok6
PubMed30373771
UniProtP51784|UBP11_HUMAN Ubiquitin carboxyl-terminal hydrolase 11 (Gene Name=USP11)

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