Structure of PDB 5oj1 Chain A

Receptor sequence
>5oj1A (length=675) Species: 171101 (Streptococcus pneumoniae R6) [Search protein sequence]
VPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNK
VAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELE
AAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMES
SLNSILAGTDGIITYLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMET
QMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWR
DILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWD
VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPT
RFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVML
EPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYG
TMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSM
SPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK
ALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE
EGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS
TVQKQDVRANTAIKDIKKITLTLGD
3D structure
PDB5oj1 Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae.
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1S6 A S337 K340 W374 N377 S395 N397 F450 Q452 G549 T550 Q552 S262 K265 W299 N302 S320 N322 F375 Q377 G474 T475 Q477
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0046677 response to antibiotic
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5oj1, PDBe:5oj1, PDBj:5oj1
PDBsum5oj1
PubMed29357220
UniProtP59676|PBPX_STRR6 Penicillin-binding protein 2X (Gene Name=pbpX)

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