Structure of PDB 5ogw Chain A

Receptor sequence
>5ogwA (length=370) Species: 137071 (Plasmodium falciparum HB3) [Search protein sequence]
VQALVVDNGSGNVKAGVAGDDAPRSVFPSIVGRPKNPGIMVGMEEKDAFV
GDEAQTKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRAAPEEHPVL
LTEAPLNPKGNRERMTQIMFESFNVPAMYVAIQAVLSLYSSGRTTGIVLD
SGDGVSHTVPIYEGYALPHAIMRLDLAGRDLTEYLMKILHERGYGFSTSA
EKEIVRDIKEKLCYIALNFDEEMKTSEQSSDIEKSYELPDGNIITVGNER
FRCPEALFQPSFLGKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVLSGGTT
MYEGIGERLTRDITTLAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQQ
MWITKEEYDESGPSIVHRKC
3D structure
PDB5ogw Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A G16 S17 N19 G159 D160 K216 E217 G305 Y309 G9 S10 N12 G152 D153 K209 E210 G298 Y302
BS02 9UE A G200 Y201 F203 N249 G193 Y194 F196 N242
BS03 9UE A H76 I78 P115 R180 H69 I71 P108 R173
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0007010 cytoskeleton organization
GO:0009665 plastid inheritance
GO:0020014 schizogony
GO:0070360 symbiont-mediated actin polymerization-dependent cell-to-cell migration in host
GO:0085017 entry into host cell by a symbiont-containing vacuole
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ogw, PDBe:5ogw, PDBj:5ogw
PDBsum5ogw
PubMed28923924
UniProtQ8I4X0|ACT1_PLAF7 Actin-1 (Gene Name=ACT1)

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