Structure of PDB 5ogk Chain A

Receptor sequence
>5ogkA (length=292) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
NSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLII
LRILGFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLT
IILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQNPGYFWMFTN
CITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSV
NLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLP
IALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQ
3D structure
PDB5ogk Structural basis of nucleotide sugar transport across the Golgi membrane.
ChainA
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GDD A Y28 M35 Y114 I265 S266 S269 Y281 K289 Y10 M17 Y93 I224 S225 S228 Y240 K248 PDBbind-CN: -logKd/Ki=5.11,IC50=7.7uM
Gene Ontology
Molecular Function
GO:0005458 GDP-mannose transmembrane transporter activity
GO:0015297 antiporter activity
Biological Process
GO:0055085 transmembrane transport
GO:1990570 GDP-mannose transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle

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Molecular Function

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Cellular Component
External links
PDB RCSB:5ogk, PDBe:5ogk, PDBj:5ogk
PDBsum5ogk
PubMed29143814
UniProtP40107|GMT1_YEAST GDP-mannose transporter 1 (Gene Name=VRG4)

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