Structure of PDB 5oel Chain A

Receptor sequence
>5oelA (length=452) Species: 83331 (Mycobacterium tuberculosis CDC1551) [Search protein sequence]
ATTTATRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGGGRGAIARG
LGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKAA
LPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTAD
GEIRHLTPTGEDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIADGDV
TASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLATVEQ
LPAKLRSEPLKFDLTLPDVFPNGLANKYTFGPIGELWYRKSGTYRGKVQN
LTQFCHPLDMFGEWNRAYGPAGFLQYQFVIPTEAVDEFKKIIGVIQASGH
YSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVSELDRRVLE
FGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFASDMARRLE
LL
3D structure
PDB5oel Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.98.3: decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003885 D-arabinono-1,4-lactone oxidase activity
GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Biological Process
GO:0035884 arabinan biosynthetic process
GO:0045227 capsule polysaccharide biosynthetic process
GO:0046677 response to antibiotic
GO:0070592 cell wall polysaccharide biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5oel, PDBe:5oel, PDBj:5oel
PDBsum5oel
PubMed28815830
UniProtP9WJF1|DPRE1_MYCTU Decaprenylphosphoryl-beta-D-ribose oxidase (Gene Name=dprE1)

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