Structure of PDB 5ody Chain A

Receptor sequence
>5odyA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB5ody Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.
ChainA
Resolution1.149 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9SK A R144 I145 A146 H158 N160 R162 W181 E184 R186 S237 G238 R32 I33 A34 H46 N48 R50 W69 E72 R74 S125 G126 MOAD: Kd=4nM
PDBbind-CN: -logKd/Ki=8.40,Kd=4.0nM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:5ody, PDBe:5ody, PDBj:5ody
PDBsum5ody
PubMed29284090
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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