Structure of PDB 5oc6 Chain A

Receptor sequence
>5oc6A (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
GVIKMAVKFDRRAYPAQITPKMCLLEWCRREKLAQPVYETVQRPLDRLFS
SIVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGR
3D structure
PDB5oc6 Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.91: tRNA-dihydrouridine(20) synthase [NAD(P)(+)].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Q367 E376 R379 S418 Q17 E26 R29 S68
BS02 rna A Q367 T369 K371 M372 L375 K420 Q424 Q17 T19 K21 M22 L25 K70 Q74
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:5oc6, PDBe:5oc6, PDBj:5oc6
PDBsum5oc6
PubMed30605527
UniProtQ9NX74|DUS2L_HUMAN tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (Gene Name=DUS2)

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