Structure of PDB 5oax Chain A

Receptor sequence
>5oaxA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
MLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB5oax Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9Q5 A R144 H158 R162 W181 E184 R186 R32 H46 R50 W69 E72 R74 MOAD: Kd=27nM
PDBbind-CN: -logKd/Ki=7.57,Kd=27nM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:5oax, PDBe:5oax, PDBj:5oax
PDBsum5oax
PubMed29284090
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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