Structure of PDB 5o9y Chain A

Receptor sequence
>5o9yA (length=429) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SFEKTPAIKIVGNKFFDSESGEQFFIKGIAYQLQRSTSYIDALADPKICL
RDIPFLKMLGVNTLRVYAIDPTKSHDICMEALSAEGMYVLLDLSEPDISI
NRENPSWDVHIFERYKSVIDAMSSFPNLLGYFAGNEVTNDHTNTFASPFV
KAAIRDAKEYISHSNHRKIPVGYSTNDDAMTRDNLARYFVCGDVKADFYG
INMYEWCGYSTYGTSGYRERTKEFEGYPIPVFFSEFGCNLVRPRPFTEVS
ALYGNKMSSVWSGGLAYMYFEEENEYGVVKINDNDGVDILPDFKNLKKEF
AKADPKGITEEEYLTVECPHIAVGVWEANEKLPETPDRSKCACLDEILPC
EIVPFGKYEEYFSYLCSKVDCSDILANGKTGEYGEFSDCSVEQKLSLQLS
KLYCKIGANDRHCPLNDKNVYFNLESLQC
3D structure
PDB5o9y Inhibitors against Fungal Cell Wall Remodeling Enzymes.
ChainA
Resolution1.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9PN A Y107 S134 P136 S139 I140 R142 Y244 Y307 Y316 Y67 S94 P96 S99 I100 R102 Y204 Y267 Y276 MOAD: Kd=4.6uM
PDBbind-CN: -logKd/Ki=5.34,Kd=4.60uM
External links
PDB RCSB:5o9y, PDBe:5o9y, PDBj:5o9y
PDBsum5o9y
PubMed29164827
UniProtQ06135|GAS2_YEAST 1,3-beta-glucanosyltransferase GAS2 (Gene Name=GAS2)

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