Structure of PDB 5o9r Chain A

Receptor sequence
>5o9rA (length=429) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SFEKTPAIKIVGNKFFDSESGEQFFIKGIAYQLQRSSYIDALADPKICLR
DIPFLKMLGVNTLRVYAIDPTKSHDICMEALSAEGMYVLLDLSEPDISIN
RENPSWDVHIFERYKSVIDAMSSFPNLLGYFAGNEVTNDHTNTFASPFVK
AAIRDAKEYISHSNHRKIPVGYSTNDDAMTRDNLARYFVCGDVKADFYGI
NMYEWCGYSTYGTSGYRERTKEFEGYPIPVFFSEFGCNLVRPRPFTEVSA
LYGNKMSSVWSGGLAYMYFEEENEYGVVKINDNDGVDILPDFKNLKKEFA
KADPKGITEEEYLTSVECPHIAVGVWEANEKLPETPDRSKCACLDEILPC
EIVPGKYEEYFSYLCSKVDCSDILANGKTGEYGEFSDCSVEQKLSLQLSK
LYCKIGANDRHCPLNDKNVYFNLESLQPC
3D structure
PDB5o9r Inhibitors against Fungal Cell Wall Remodeling Enzymes.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A E245 C247 E204 C206
BS02 BGC A D217 R222 E245 D176 R181 E204
BS03 BGC A N216 D217 N175 D176
BS04 9PK A Q60 Y107 S134 P136 S139 I140 R142 Y244 E275 Y307 Q32 Y66 S93 P95 S98 I99 R101 Y203 E234 Y266 MOAD: Kd=4.09uM
PDBbind-CN: -logKd/Ki=5.39,Kd=4.09uM
External links
PDB RCSB:5o9r, PDBe:5o9r, PDBj:5o9r
PDBsum5o9r
PubMed29164827
UniProtQ06135|GAS2_YEAST 1,3-beta-glucanosyltransferase GAS2 (Gene Name=GAS2)

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