Structure of PDB 5o9p Chain A

Receptor sequence
>5o9pA (length=435) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SFEKTPAIKIVGNKFFDSESGEQFFIKGIAYQLQRSGAFETSYIDALADP
KICLRDIPFLKMLGVNTLRVYAIDPTKSHDICMEALSAEGMYVLLDLSEP
DISINRENPSWDVHIFERYKSVIDAMSSFPNLLGYFAGNEVTNDHTNTFA
SPFVKAAIRDAKEYISHSNHRKIPVGYSTNDDAMTRDNLARYFVCGDVKA
DFYGINMYEWCGYSTYGTSGYRERTKEFEGYPIPVFFSEFGCNLVRPRPF
TEVSALYGNKMSSVWSGGLAYMYFEEENEYGVVKINDNDGVDILPDFKNL
KKEFAKADPKGITEEEYLTESVECPHIAVGVWEANEKLPETPDRSKCACL
DEILPCEIVPGKYEEYFSYLCSKVDCSDILANGKTGEYGEFSDCSVEQKL
SLQLSKLYCKIGANDRHCPLNDKNVYFNLESLQPC
3D structure
PDB5o9p Inhibitors against Fungal Cell Wall Remodeling Enzymes.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9P8 A Y107 D132 S134 P136 S139 I140 R142 V177 Y244 E275 Y307 Y316 Y71 D96 S98 P100 S103 I104 R106 V141 Y208 E239 Y271 Y280 MOAD: Kd=8.06uM
PDBbind-CN: -logKd/Ki=5.09,Kd=8.06uM
External links
PDB RCSB:5o9p, PDBe:5o9p, PDBj:5o9p
PDBsum5o9p
PubMed29164827
UniProtQ06135|GAS2_YEAST 1,3-beta-glucanosyltransferase GAS2 (Gene Name=GAS2)

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