Structure of PDB 5o6i Chain A

Receptor sequence

>5o6iA (length=191) Species: 2275 (Desulfurococcus mucosus) [Search protein sequence]

ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHFAP
LMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFTNMLERIRLCNMR
EQIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLD
DHRHGVYVLNISLRDRIKFVHTILSSHLNPLPPEAAALEHH

3D structure

PDB

5o6i Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI.

Chain

Resolution

2.25 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	G20 D21 G22 Y25 Y29 K30 R33 R37 T41 Q42 K43 T76 R77 R124 T150 H152 D154 H156 R157 S166 L167	G16 D17 G18 Y21 Y25 K26 R29 R33 T37 Q38 K39 T72 R73 R120 T146 H148 D150 H152 R153 S162 L163
BS02	dna	A	N32 R33 S34 E35 Y36 R37 S67 K68 Q70 D75 R81 S83 K85 A116 D119 R126 W128 N129 K130 D155 H158 V160	N28 R29 S30 E31 Y32 R33 S63 K64 Q66 D71 R77 S79 K81 A112 D115 R122 W124 N125 K126 D151 H154 V156
BS03	MN	A	D21 A116	D17 A112
BS04	MN	A	G20 E117	G16 E113

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

	Biological Process
GO:0006314	intron homing
GO:0016539	intein-mediated protein splicing

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Molecular Function

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Biological Process

External links

PDB	RCSB:5o6i, PDBe:5o6i, PDBj:5o6i
PDBsum	5o6i
PubMed	29177929
UniProt	P21505\|DMO1_DESMO Homing endonuclease I-DmoI

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